Grin2a (NM_008170) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR227135L3V
- LentiORF®
Lenti ORF particles, Grin2a (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2A (epsilon 1) (Grin2a), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
Interest in protein/lysate? Submit request here!
Product Images
Frequently bought together (3)
Other products for "Grin2a"
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Grin2a |
Synonyms | GluN2A; NMDAR2A; NR2A |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_008170 |
ORF Size | 4392 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227135).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008170.2 |
RefSeq Size | 4512 bp |
RefSeq ORF | 4395 bp |
Locus ID | 14811 |
UniProt ID | P35436 |
Cytogenetics | 16 5.28 cM |
Gene Summary | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium (PubMed:1374164). Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinetics than channels formed by GRIN1 and GRIN2B (By similarity). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (PubMed:7816096, PubMed:8987814).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.