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Home cDNA Clone TrueORF All Mlkl ORF Clones

Mlkl (NM_029005) Mouse cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MR207406L2 Lenti ORF clone of Mlkl (mGFP-tagged) - Mouse mixed lineage kinase domain-like (Mlkl), (10ug), 10µg   
$830
3-4 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
0 5 weeks
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Clone Modification
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TrueORF Data for MR207406L2
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Vector: pLenti-C-mGFP   Change vector? Tag: C-terminal mGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1395 bp
Predicted Protein MW: kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq Explanation: NM_029005.1, NP_083281 RefSeq Size: 1703 RefSeq ORF: 1395
Synonyms : 9130019I15Rik
LocusID: 74568 Cytogenetic: 8|8 D3
Gene Summary: This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015].

 

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