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Home cDNA Clone TrueORF All Lrrk2 ORF Clones

Lrrk2 (NM_025730) Mouse cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MG225348 Lrrk2 (GFP-tagged) - Mouse leucine-rich repeat kinase 2 (Lrrk2), (10ug), 10µg
7-8 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for MG225348
Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 7584 bp
Predicted Protein MW: kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq: NM_025730.3, NP_080006
RefSeq Size: 8231 RefSeq ORF: 7584
Synonyms : 4921513O20Rik; 9330188B09Rik; AW561911; cI-46; D630001M17Rik; Gm927
LocusID: 66725 Cytogenetic: 15|15 F1
Summary: Phosphorylates PRDX3 (By similarity). May also have GTPase activity (By similarity). Has a regulatory role in autophagy induction through a calcium-dependent activation of the CaMKK/AMPK signaling pathway (By similarity). The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. [UniProtKB/Swiss-Prot Function]


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