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Home cDNA Clone TrueORF All Tnfrsf10b ORF Clones

Tnfrsf10b (NM_020275) Mouse cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MG205945 Tnfrsf10b (GFP-tagged) - Mouse tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), 10µg
$420
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for Tnfrsf10b (NM_020275)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody
TrueORF Data for MG205945
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1145 bp
Predicted Protein MW: kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq: NM_020275.3, NP_064671
RefSeq Size: 3142 RefSeq ORF: 1146
Synonyms : DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB
LocusID: 21933 Cytogenetic: 14 D2|14
Summary: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. [UniProtKB/Swiss-Prot Function]

 

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