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Home MicroRNA 3' UTR Clones

CCL5 (NM_002985) 3’-UTR clone in pMirTarget

Specifications Citations (1) Related Products Product Documents
Cat. No. Description Price Availability  
SC210875 3`UTR clone of chemokine (C-C motif) ligand 5 (CCL5) for miRNA target validation $510.00 4 weeks * Add to Shopping Cart
OriGene TrueClone Data
Vector:pMirTarget Insert Size: 874 Restriction Site: SgfI-MluI
Sequence Data:Insert Sequence
OTI Disclaimer:Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components:The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data
RefSeq:NM_002985.2
Synonyms :D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228
Locus ID:6352
Summary:This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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