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Home MicroRNA 3' UTR Clones

CYP27B1 (NM_000785) 3’-UTR clone in pMirTarget

Specifications Citations Related Products Product Documents
Cat. No. Description Price Availability  
SC210195 3`UTR clone of cytochrome P450 family 27 subfamily B polypeptide 1 (CYP27B1) nuclear gene encoding mitochondrial protein for miRNA target validation $495.00 1 weeks * Add to Shopping Cart
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Also for CYP27B1 (NM_000785)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
OriGene TrueClone Data
Vector:pMirTarget Insert Size: 832 Restriction Site: SgfI-MluI
Sequence Data:Insert Sequence
OTI Disclaimer:Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components:The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data
RefSeq:NM_000785.3
Synonyms :CP2B; CYP1; CYP1alpha; CYP27B; P450c1; PDDR; VDD1; VDDR; VDDRI; VDR
Locus ID:1594
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008].

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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