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Home Recombinant Human Proteins ZAP70 Heavy-labeled protein

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ZAP70 Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH308838 NM_001079 ZAP70 MS Standard C13 and N15-labeled recombinant protein (NP_001070), 10 ug $1500 3 weeks
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Also for ZAP70 (NM_001079)
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OriGene Data
Expression Host:Human HEK293 cells Predicted MW:69.7 kDa
Expression TrueORF clone:RC208838 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_001070 RefSeq Size: 2450 RefSeq ORF: 1860
Synonyms : SRK; STCD; STD; TZK; ZAP-70
LocusID: 7535 Cytogenetic: 2q12  
Summary: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

 

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