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Home Recombinant Human Proteins OAS1 Heavy-labeled protein

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OAS1 Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH300696 NM_002534 OAS1 MS Standard C13 and N15-labeled recombinant protein (NP_002525), 10 ug $1500 3 weeks
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OriGene Data
Expression Host:Human HEK293 cells Predicted MW:41.6 kDa
Expression TrueORF clone:RC200696 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_002525 RefSeq Size: 1470 RefSeq ORF: 1095
Synonyms : IFI-4; OIAS; OIASI
LocusID: 4938 Cytogenetic: 12q24.2  
Summary: This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, Feb 2016].

 

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