FOXA2 (NM_021784) Human Untagged Clone

CAT#: SC122913

FOXA2 (untagged)-Human forkhead box A2 (FOXA2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOXA2
• Synonyms: HNF-3-beta; HNF3B; TCF3B
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021784 edited
  GTGGCTGTTAAATTTTAAACTGCCATGCACTCGGCTTCCAGTATGCTGGGAGCGGTGAAG
  ATGGAAGGGCACGAGCCGTCCGACTGGAGCAGCTACTATGCAGAGCCCGAGGGCTACTCC
  TCCGTGAGCAACATGAACGCCGGCCTGGGGATGAACGGCATGAACACGTACATGAGCATG
  TCGGCGGCCGCCATGGGCAGCGGCTCGGGCAACATGAGCGCGGGCTCCATGAACATGTCG
  TCGTACGTGGGCGCTGGCATGAGCCCGTCCCTGGCGGGGATGTCCCCCGGCGCGGGCGCC
  ATGGCGGGCATGGGCGGCTCGGCCGGGGCGGCTGGCGTGGCGGGCATGGGGCCGCACTTG
  AGTCCCAGCCTGAGCCCGCTCGGGGGGCAGGCGGCCGGGGCCATGGGCGGCCTGGCCCCC
  TACGCCAACATGAACTCCATGAGCCCCATGTACGGGCAGGCGGGCCTGAGCCGCGCCCGC
  GACCCCAAGACCTACAGGCGCAGCTACACGCACGCAAAGCCGCCCTACTCGTACATCTCG
  CTCATCACCATGGCCATCCAGCAGAGCCCCAACAAGATGCTGACGCTGAGCGAGATCTAC
  CAGTGGATCATGGACCTCTTCCCCTTCTACCGGCAGAACCAGCAGCGCTGGCAGAACTCC
  ATCCGCCACTCGCTCTCCTTCAACGACTGTTTCCTGAAGGTGCCCCGCTCGCCCGACAAG
  CCCGGCAAGGGCTCCTTCTGGACCCTGCACCCTGACTCGGGCAACATGTTCGAGAACGGC
  TGCTACCTGCGCCGCCAGAAGCGCTTCAAGTGCGAGAAGCAGCTGGCGCTGAAGGAGGCC
  GCAGGCGCCGCCGGCAGCGGCAAGAAGGCGGCCGCCGGGGCCCAGGCCTCACAGGCTCAA
  CTCGGGGAGGCCGCCGGGCCGGCCTCCGAGACTCCGGCGGGCACCGAGTCGCCTCACTCG
  AGCGCCTCCCCGTGCCAGGAGCACAAGCGAGGGGGCCTGGGAGAGCTGAAGGGGACGCCG
  GCTGCGGCGCTGAGCCCCCCAGAGCCGGCGCCCTCTCCCGGGCAGCAGCAGCAGGCCGCG
  GCCCACCTGCTGGGCCCGCCCCACCACCCGGGCCTGCCGCCTGAGGCCCACCTGAAGCCG
  GAACACCACTACGCCTTCAACCACCCGTTCTCCATCAACAACCTCATGTCCTCGGAGCAG
  CAGCACCACCACAGCCACCACCACCACCAGCCCCACAAAATGGACCTCAAGGCCTACGAA
  CAGGTGATGCACTACCCCGGCTACGGTTCCCCCATGCCTGGCAGCTTGGCCATGGGCCCG
  GTCACGAACAAAACGGGCCTGGACGCCTCGCCCCTGGCCGCAGATACCTCCTACTACCAG
  GGGGTGTACTCCCGGCCCATTATGAACTCCTCTTAAGAAGACGACGGCTTCAGGCCCGGC
  TAACTCTGGCACCCCGGATCGAGGATAAGTGAGAGAGCAAGTGGGGGTCGAGACTTTGGG
  GAGACGGTGTTGCAGAGACGCAAGGGAGAAGAAATCCATAACACCCCCACCCCAACACCC
  CCAAGACAGCAGTCTTCCTTCACCCGCTGCAGCTGTTCCGTCCCAAACAGAGGGCCACAC
  AGATACCCCACGTTCTATATAAGGAGGAAAACGGGAAAGAATATAAAGTTAAAAAAAAGC
  CTCCGGTTTCCACTACTGTGTAGACTCCTGCTTCTTCAAGCACCTGCAGATTCTGATTTT
  TTTGTTGTTGTTGTTCTCCTCCATTGCTGTTGTTGCAGGGAAGTCTTACTTAAAAAAAAA
  AAAAAACTTTTGTGAGTGACTCGGTGTAAAACCATGTAGTTTTAACAGAACCAGAGGGTT
  GTACTATTGTTTAAAAACAGGAAAAAAAATAATGTAAGGGTCTGTTGTAAATGACCAAGA
  AAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021784 unedited
  GGGAACTTGGTTNTTGTATCCGACTTTCTGATAGGGCGGCCGCGCAATTCGCACGGGGTG
  GCTGTTTTATTTTAAACTGCCATGCACTCGGCTTCCAGTATGCTGGGAGCGGTGAAGATG
  GAAGGGCACGAGCCGTCCGACTGGAGCAGCTACTATGCAGAGCCCGAGGGCTACTCCTCC
  GTGAGCAACATGAACGCCGGCCTGGGGATGAACGGCATGAACACGTACATGAGCATGTCG
  GCGGCCGCCATGGGCAGCGGCTCGGGCAACATGAGCGCGGGCTCCATGAACATGTCGTCG
  TACGTGGGCGCTGGCATGAGCCCGTCCCTGGCGGGGATGTCCCCCGGCGCGGGCGCCATG
  GCGGGCATGGGCGGCTCGGCCGGGGCGGCTGGCGTGGCGGGCATGGGGCCGCACTTGAGT
  CCCAGCCTGAGCCCGCTCGGGGGGCAGGCGGCCGGGGCCATGGGCGGCCTGGCCCCCTAC
  GCCAACATGAACTCCATGAGCCCCATGTACGGGCAGGCGGGCCTGAGCCGCGCCCGCGAC
  CCCAAGACCTACAGGCGCAGCTACACGCACGCAAAGCCGCCCTACTCGTACATCTCGCTC
  ATCACCATGGCCATCCAGCAGAGCCCCAACAAGATGCTGACGCTGAGCGAGATCTACCAG
  TGGATCATGGACCTCTTCCCCTTCTACCGGCAGAACCAGCAGCGCTGGCAGAACTCCATC
  CGCCACTCGCTCTCCTTCAACGACTGTTTCCTGAAGGTGCCCCGCTCGCCCGACAAGCCC
  GGCAAGGGCTCCTTCTGGACCCTGCACCCTNGACTCGGCACATGTTCGAGAACGGCTGCT
  ACCTGCGCCGCCAGAAGCGCTTCAAGTGCGAGAAGCAGCTGGCGCTGAAGGAGGCCGCAN
  GCGCCCGCCGGCAGCGN
  
• Restriction Sites: Please inquire
• ACCN: NM_021784
• Insert Size: 1946 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021784.3, NP_068556.1
• RefSeq Size: 2428 bp
• RefSeq ORF: 1374 bp
• Locus ID: 3170
• UniProt ID: Q9Y261
• Cytogenetics: 20p11.21
• Protein Families: Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young
• Gene Summary: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).