SLC9A6 (NM_006359) Human Untagged Clone

CAT#: SC116146

SLC9A6 (untagged)-Human solute carrier family 9 (sodium/hydrogen exchanger), member 6 (SLC9A6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC9A6
• Synonyms: MRSA; NHE6
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006359, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCGGCGCGGCTGGCGGCGGGCACCCCTCCGCCGTGGCGTCGGCAGCAGTCCCCGAGCCCGCAGGC
  TCATGCGGCCCCTTTGGTTGCTCCTCGCAGTGGGCGTCTTTGACTGGGCAGGGGCTTCGGACGGCGGCGG
  CGGAGAGGCTAGAGCCATGGACGAGGAGATCGTGTCCGAGAAGCAAGCCGAGGAGAGCCACCGGCAGGAC
  AGCGCCAACCTGCTCATCTTCATCCTGCTGCTCACCCTCACCATTCTCACAATCTGGCTCTTCAAGCACC
  GCCGGGCCCGCTTCCTGCACGAAACCGGCCTGGCTATGATTTATGGTCTTTTGGTGGGCCTTGTGCTTCG
  GTATGGCATTCATGTTCCGAGTGATGTAAATAATGTGACCCTGAGCTGTGAAGTGCAGTCAAGTCCAACT
  ACCTTACTGGTTACTTTTGATCCAGAAGTATTTTTCAACATATTACTTCCTCCTATCATATTTTATGCAG
  GTTATAGCCTGAAAAGGAGACATTTTTTTCGAAATCTTGGGTCTATCCTAGCATACGCTTTTCTTGGAAC
  AGCAATTTCTTGTTTCGTTATTGGGTCAATAATGTATGGCTGTGTAACGCTGATGAAGGTAACGGGACAA
  CTTGCAGGAGATTTTTACTTTACAGATTGCCTACTGTTTGGTGCCATTGTATCAGCAACTGATCCAGTGA
  CTGTTCTTGCTATATTCCACGAGCTTCAAGTTGATGTTGAACTCTATGCACTTCTTTTTGGTGAAAGTGT
  CCTCAATGATGCTGTTGCCATAGTGCTGTCCTCCTCAATAGTGGCATACCAGCCAGCTGGAGACAACAGT
  CACACCTTTGATGTCACAGCGATGTTCAAGTCTATTGGGATCTTCCTTGGAATCTTCAGTGGATCTTTTG
  CAATGGGTGCTGCTACTGGAGTGGTGACAGCTTTAGTGACAAAGTTCACCAAATTACGGGAGTTCCAGTT
  GTTGGAGACAGGCCTGTTCTTCTTGATGTCCTGGAGTACCTTCCTCTTGGCTGAAGCATGGGGCTTCACA
  GGTGTAGTTGCAGTATTGTTTTGTGGCATCACACAAGCACATTATACGTATAATAATTTGTCCACGGAGT
  CTCAGCATAGAACTAAACAGTTGTTTGAGCTTCTCAATTTCTTGGCAGAGAATTTCATCTTCTCCTACAT
  GGGGCTGACACTGTTCACCTTCCAGAACCATGTCTTTAACCCAACATTTGTAGTAGGAGCATTTGTTGCT
  ATTTTCTTGGGAAGAGCTGCCAATATTTACCCCTTGTCCCTCTTACTTAATTTGGGTAGAAGAAGTAAGA
  TTGGATCAAATTTTCAACACATGATGATGTTTGCTGGCCTTCGTGGTGCAATGGCATTTGCCTTGGCCAT
  TCGAGATACTGCCACTTATGCACGGCAAATGATGTTCAGCACCACGCTTCTGATTGTGTTTTTTACCGTG
  TGGGTATTTGGTGGTGGCACCACTGCAATGCTGTCATGCTTGCATATCAGGGTTGGTGTTGATTCAGACC
  AAGAACACTTGGGTGTTCCTGAAAATGAAAGGAGAACTACCAAAGCAGAGAGTGCTTGGCTTTTCCGGAT
  GTGGTACAACTTTGATCATAACTATCTGAAGCCTCTGCTGACCCACAGCGGGCCTCCGCTGACAACAACA
  CTCCCTGCCTGCTGTGGACCCATCGCCAGGTGCCTCACCAGCCCCCAGGCTTACGAAAACCAGGAACAGT
  TGAAAGATGATGATTCTGATCTTATTCTCAATGATGGTGACATCAGTTTGACATATGGAGATTCTACTGT
  GAACACTGAACCGGCCACATCCAGCGCCCCAAGGAGATTTATGGGAAACAGTTCTGAAGATGCCTTGGAT
  CGGGAGCTTGCATTTGGGGACCATGAACTGGTCATTCGAGGAACACGCCTGGTTCTTCCAATGGATGATT
  CTGAACCCCCGCTAAATTTGTTAGATAATACGAGACATGGTCCAGCCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006359 unedited
  GCATTTTGTATACGACTCCTATAGGCGGCCGCGAATTCGGCACGAGGGCGGGGGGAGACA
  TGGCTCGGCGCGGCTGGCGGCGGGCACCCCTCCGCCGTGGCGTCGGCAGCAGTCCCCGAG
  CCCGCAGGCTCATGCGGCCCCTTTGGTTGCTCCTCGCAGTGGGCGTCTTTGACTGGGCAG
  GGGCTTCGGACGGCGGCGGCGGAGAGGCTAGAGCCATGGACGAGGAGATCGTGTCCGAGA
  AGCAAGCCGAGGAGAGCCACCGGCAGGACAGCGCCAACCTGCTCATCTTCATCCTGCTGC
  TCACCCTCACCATTCTCACAATCTGGCTCTTCAAGCACCGCCGGGCCCGCTTCCTGCACG
  AAACCGGCCTGGCTATGATTTATGGTCTTTTGGTGGGCCTTGTGCTTCGGTATGGCATTC
  ATGTTCCGAGTGATGTAAATAATGTGACCCTGAGCTGTGAAGTGCAGTCAAGTCCAACTA
  CCTTACTGGTAAATGTTAGTGGAAAATTTTATGAGTATATGCTGAAAGGAGAGATTAGTT
  CACATGAACTCAATAATGTTCAAGATAATGAAATGCTTAGAAAGGTTACTTTTGATCCAG
  AAGTATTTTTCAACATATTACTTCCTCCTATCATATTTTATGCAGGTTATAGCCTGGAAA
  GGAGACATTCTTTTCGAAATCTGGGTCTATCCTAGCATACGCTTTTCTTGGAACAGCAAT
  TTCTTGTTTCGTTATTGCGTCACTAATGTATGGCTGTGTAACGCTGATGAAAGTAACGGG
  ACAACTTGCCAGAGAATTTTACTTTACAGATTGCCTACTGGTTGGTGCCCTTGTATCAGC
  AACTGATCCAGNGACTGGTTTTGCTTTATTCACGAGCTTCAGNTGATGTTGAACTCTATG
  CCCTCCCTTTTGTGAAAGGGTGCCCAATGATGCTGTTGCCACTAAGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006359 unedited
  ACTTTGGACCGGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTGGGTATTTG
  CAAGGCTATAACTTTTTTAATGACAGATTTTCCTAAAAGAAACCACTATAACATCTGTCC
  AAGTACTCCAGGAGAAAACAAAAAATACATAAAGATTAAAAGTCTATTACTTTAACAGCA
  CATTGCCAAACACGGACAACTAGGATAAATGCCAAGAAACCTTAAAAAATAACTTTAAAA
  GATGCAACGTTCAAGCCATTCAAACGCGTAGGTTCCACAAACAACAGGAAAACAAGTCCA
  AGAGCAGTTCTACTTGTGCATGATGGTAACTCAGACTGTACTTCATCAAAGTTCATTCAG
  GTGTTTCATAGGCGTCTGAGCAGAGTTTGTTTTTTCTTCCTTGCTTGGAGATGTGTACAC
  AGATTAGAGGAGAGGAAAGTCTTCCAGATGCTGATGTAAGCACAGCAGGCTTGGTTCCCC
  TTGATAAAGTATGAAGGCAGATTTAGTTGACTCAAGCTTTATCAGTTTCCCTAGTGAAAA
  GTCTTATGCATGCTGAAATAGACGAGTTACTGAATNTGTCATGCGAAGTATTTACATAAA
  GTGAGGTCAGTAACCCGACAGAATAAAAAAGGTAGTTGTAAATTATTGTATAACCTTTTA
  CACTTGAATAACTTGTGGGGAAGTGACACTGGACGTCAACTCCTCAACATACTTAACAAG
  AATTTTACTGCGTGAAGAGCCACATCATGTAAAATACACGTATGGGAGGGATCCTGCATA
  CAGGAAAGTCGCTCCACTACATACAATGGCTTGCCAACAGTCAGCTGCCCGAAGGGTACA
  CATTAGATNCCCTAATTCAAGGATGTTGCATACCAGAAGATGCTTTCGAATAAGTACTGG
  TTGGTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006359
• Insert Size: 4260 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006359.1, NP_006350.1
• RefSeq Size: 4452 bp
• RefSeq ORF: 2010 bp
• Locus ID: 10479
• UniProt ID: Q92581
• Cytogenetics: Xq26.3
• Domains: Na_H_Exchanger
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cardiac muscle contraction
• Gene Summary: This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic cognitive disability, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.