TACI (TNFRSF13B) (NM_012452) Human Untagged Clone

CAT#: SC115358

TNFRSF13B (untagged)-Human tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TACI
• Synonyms: CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF14B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115358 sequence for NM_012452 edited (data generated by NextGen Sequencing)
  ATGAGTGGCCTGGGCCGGAGCAGGCGAGGTGGCCGGAGCCGTGTGGACCAGGAGGAGCGC
  TTTCCACAGGGCCTGTGGACAGGGGTGGCTATGAGATCCTGCCCCGAAGAGCAGTACTGG
  GATCCTCTGCTGGGTACCTGCATGTCCTGCAAAACCATTTGCAACCATCAGAGCCAGCGC
  ACCTGTGCAGCCTTCTGCAGGTCACTCAGCTGCCGCAAGGAGCAAGGCAAGTTCTATGAC
  CATCTCCTGAGGGACTGCATCAGCTGTGCCTCCATCTGTGGACAGCACCCTAAGCAATGT
  GCATACTTCTGTGAGAACAAGCTCAGGAGCCCAGTGAACCTTCCACCAGAGCTCAGGAGA
  CAGCGGAGTGGAGAAGTTGAAAACAATTCAGACAACTCGGGAAGGTACCAAGGATTGGAG
  CACAGAGGCTCAGAAGCAAGTCCAGCTCTCCCGGGGCTGAAGCTGAGTGCAGATCAGGTG
  GCCCTGGTCTACAGCACGCTGGGGCTCTGCCTGTGTGCCGTCCTCTGCTGCTTCCTGGTG
  GCGGTGGCCTGCTTCCTCAAGAAGAGGGGGGATCCCTGCTCCTGCCAGCCCCGCTCAAGG
  CCCCGTCAAAGTCCGGCCAAGTCTTCCCAGGATCACGCGATGGAAGCCGGCAGCCCTGTG
  AGCACATCCCCCGAGCCAGTGGAGACCTGCAGCTTCTGCTTCCCTGAGTGCAGGGCGCCC
  ACGCAGGAGAGCGCAGTCACGCCTGGGACCCCCGACCCCACTTGTGCTGGAAGGTGGGGG
  TGCCACACCAGGACCACAGTCCTGCAGCCTTGCCCACACATCCCAGACAGCGGCCTTGGC
  ATTGTGTGTGTGCCTGCCCAGGAGGGGGGCCCAGGTGCATAA
  
  Clone variation with respect to NM_012452.2
  81 g=>a;831 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012452 unedited
  CACGAGAATAAGCATCCTTGATAATGAGTGGCCTGGGCCGGAGCAGGCGAGGTGGCCGGA
  GCCGTGTGGACCAGGAGGAGCGCTTTCCACAGGGCCTGTGGACAGGGGTGGCTATGAGAT
  CCTGCCCCGAAGAGCAGTACTGGGATCCTCTGCTGGGTACCTGCATGTCCTGCAAAACCA
  TTTGCAACCATCAGAGCCAGCGCACCTGTGCAGCCTTCTGCAGGTCACTCAGCTGCCGCA
  AGGAGCAAGGCAAGTTCTATGACCATCTCCTGAGGGACTGCATCAGCTGTGCCTCCATCT
  GTGGACAGCACCCTAAGCAATGTGCATACTTCTGTGAGAACAAGCTCAGGAGCCCAGTGA
  ACCTTCCACCAGAGCTCAGGAGACAGCGGAGTGGAGAAGTTGAAAACAATTCAGACAACT
  CGGGAAGGTACCAAGGATTGGAGCACAGAGGCTCAGAAGCAAGTCCAGCTCTCCCGGGGC
  TGAAGCTGAGTGCAGATCAGGTGGCCCTGGTCTACAGCACGCTGGGGCTCTGCCTGTGTG
  CCGTCCTCTGCTGCTTCCTGGTGGCGGTGGCCTGCTTCCTCAAGAAGAGGGGGGATCCCT
  GCTCCTGCCAGCCCCGCTCAAGGCCCCGTCAAAGTCCGGCCAAGTCTTCCCAGGATCACG
  CGATGGAAGCCGGCAGCCCTGTGAGCACATCCCCCGAGCCAGTGGAGACCTGCAGCTTCT
  GCTTCCCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012452 unedited
  TCCATTCGATCATTGGATGATGGCAACTTNCCAGGNCCAGAGAAAGCACTGGGGNAGGGT
  CACAGGGCAGCCACCCGGGTATCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATCTA
  GAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGG
  AGGAAAGGCAACCGCCAAAGGTTTTATTCCCCAGGAGAGAGGGGCCCTCGGGGGCTGGGA
  ACAACAGGCCCCAAGACTTTATTGCCCGTGTGGTTAGGTGAAGACCACCTACAGCTGCCC
  TGGGAACTGGGACTCAAAAGGCCCCGACCCCCGGGTCTATCTCTCTCTGGCCCTCTCTCC
  CTCTCTGGCTCTCTGCCTCTCTCCCTCTTTGGCTCTCTCCCTCTTTGGCTCTCTCCTTCT
  GGGCCGGGCCCTTTCCTTCTCTGCCCCTTTCCCTCTCTGGCTCTCTTCCCCTCTGGCTCT
  CTCTCCCTCTGGCTCTCTCTCCCTCTCTGGCTCCTCTGGTTCTCTCCCTCTCTGCCTCCC
  CTGGCTCTCTCTCCTAAAAAATCTCTCCCCTCTCCCCAACTTTTTTTTTTTCTCCCCTCC
  TTTCCATCTTTCTCCCTCCTCCTTTCCCTCCCTGACCCCCATTTAAGCCCCTGGGCCCCC
  CTCCTGGGCAGGCACACAAACAATGCCAAGGCCGCTGTCTGGGATGTGTGGGCAAGGCCG
  CAAGACTGTGGTCCCGGTGTGGCCACCCCACCTTCCAACACAATGGGGGTCGGGGGTCCC
  AAGCGTGAATGCGCCTTCCGGGGGGGGCCCCCTGCACTCAAGGAAGCAGAAGCTGCCCGT
  CCCCCCTTCTGGGGGGATGTTCCCAAAAGGGCTGCCGGGCTTCAAGGGGGGAACCGGGGA
  AAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012452
• Insert Size: 1500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012452.2, NP_036584.1
• RefSeq Size: 1377 bp
• RefSeq ORF: 882 bp
• Locus ID: 23495
• UniProt ID: O14836
• Cytogenetics: 17p11.2
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Primary immunodeficiency
• Gene Summary: The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]