SERPINE2 (NM_006216) Human Untagged Clone

CAT#: SC100408

SERPINE2 (untagged)-Human serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SERPINE2
• Synonyms: GDN; GDNPF; PI-7; PI7; PN-1; PN1; PNI
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100408 sequence for NM_006216 edited (data generated by NextGen Sequencing)
  ATGAACTGGCATCTCCCCCTCTTCCTCTTGGCCTCTGTGACGCTGCCTTCCATCTGCTCC
  CACTTCAATCCTCTGTCTCTCGAGGAACTAGGCTCCAACACGGGGATCCAGGTTTTCAAT
  CAGATTGTGAAGTCGAGGCCTCATGACAACATCGTGATCTCTCCCCATGGGATTGCGTCG
  GTCCTGGGGATGCTTCAGCTGGGGGCGGACGGCAGGACCAAGAAGCAGCTCGCCATGGTG
  ATGAGATACGGCGTAAATGGAGTTGGTAAAATATTAAAGAAGATCAACAAGGCCATCGTC
  TCCAAGAAGAATAAAGACATTGTGACAGTGGCTAACGCCGTGTTTGTTAAGAATGCCTCT
  GAAATTGAAGTGCCTTTTGTTACAAGGAACAAAGATGTGTTCCAGTGTGAGGTCCGGAAT
  GTGAACTTTGAGGATCCAGCCTCTGCCTGTGATTCCATCAATGCATGGGTTAAAAATGAA
  ACCAGGGATATGATTGACAATCTGCTGTCCCCAGATCTTATTGATGGTGTGCTCACCAGA
  CTGGTCCTCGTCAATGCAGTGTATTTCAAGGGTCTGTGGAAATCACGGTTCCAACCCGAG
  AACACAAAGAAACGCACTTTCGTGGCAGCCGACGGGAAATCCTATCAAGTGCCAATGCTG
  GCCCAGCTCTCCGTGTTCCGGTGTGGGTCGACAAGTGCCCCCAATGATTTATGGTACAAC
  TTCATTGAACTGCCCTACCACGGGGAAAGCATCAGCATGCTGATTGCACTGCCGACTGAG
  AGCTCCACTCCGCTGTCTGCCATCATCCCACACATCAGCACCAAGACCATAGACAGCTGG
  ATGAGCATCATGGTGCCCAAGAGGGTGCAGGTGATCCTGCCCAAGTTCACAGCTGTAGCA
  CAAACAGATTTGAAGGAGCCGCTGAAAGTTCTTGGCATTACTGACATGTTTGATTCATCA
  AAGGCAAATTTTGCAAAAATAACAANNNGGTCAGAAAACCTCCATGTTTCTCATATCTTG
  CAAAAAGCAAAAATTGAAGTCAGTGAAGATGGAACCAAAGCTTCAGCAGCAACAACTGCA
  ATTCTCATTGCAAGATCATCGCCTCCCTGGTTTATAGTAGACAGACCTTTTCTGTTTTTC
  ATCCGACATAATCCTACAGGTGCTGTGTTATTCATGGGGCAGATAAACAAACCCTGA
  
  Clone variation with respect to NM_006216.3
  555 c=>t;986 c=>n;987 a=>n;988 g=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006216 unedited
  NCGGTCAGCATATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGCCAGG
  CTCCCGCTCCGGTTGCGGCCGCACCGCCCTCCGCGGCCGCCCCCTGGGGATCCAGCGAGC
  GCGGTCGTCCTTGGTGGAAGGAACCATGAACTGGCATCTCCCCCTCTTCCTCTTGGCCTC
  TGTGACGCTGCCTTCCATCTGCTCCCACTTCAATCCTCTGTCTCTCGAGGAACTAGGCTC
  CAACACGGGGATCCAGGTTTTCAATCAGATTGTGAAGTCGAGGCCTCATGACAACATCGT
  GATCTCTCCCCATGGGATTGCGTCGGTCCTGGGGATGCTTCAGCTGGGGGCGGACGGCAG
  GACCAAGAAGCAGCTCGCCATGGTGATGAGATACGGCGTAAATGGAGTTGGTAAAATATT
  AAAGAAGATCAACAAGGCCATCGTCTCCAAGAAGAATAAAGACATTGTGACAGTGGCTAA
  CGCCGTGTTTGTTAAGAATGCCTCTGAAATTGAAGTGCCTTTTGTTACAAGGAACAAAGA
  TGTGTTCCAGTGTGAGGTCCGGAATGTGAACTTTGAGGATCCAGCCTCTGCCTGTGATTC
  CATCAATGCATGGGTTAAAAATGAAACCAGGGATATGATTGACAATCTGCTGTCCCCAGA
  TCTTATTGATGGTGTGCTCACCAGACTGGTCCTCGTCAATGCAGTGTATTTCAAGGGTCT
  GTGGAAATCACGGTTCCAACCCGAGACACAAAGAAACGCACTTTCGTGGCAGCCGACGGG
  AAATCCTATCAAGTGCCAATGCTGGCCCAGCTCTCCGTGTNCCCGGTGTGGGTCCGACAG
  TGCCCCCATGATTTATGGTACAACTTCATTGAACTGCCCTACACGGNGAAAGCATCANCA
  TGCTGATTGCACTGCCGACTGANAAGCTCACTNCGCTGTCTGCCATCATCCACACATNAG
  CACAGAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006216 unedited
  AGCTNTGNNACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTACTACTC
  ATAACAGTTTATTTTTACTTTGTACAAAATACAAAAATGCAAATCCAAGGAGTACAGACC
  AGTAGTGACAGGCACACTGCACAACAGCAACCTTGTCTAGCAAGACAGGAGTTTTTTAAA
  TTTTATTTTAGTGAATACATGCATTATATAAAACAACAACAACAACAACAACAAAAACAC
  AAAGAGGCTAGAGATTTCACCGTTTCTACCCCCAAAATAACGCTTGCTATCAAGACTTTG
  GAGGGGGATGGGGGAAAAGAATTTAAAAGGCAAATAATTTTTTTTTCATAAAAAGTAAAA
  GCTACCATAAAACATTTTTTTTTCTGTCACACTGATTAAATTTCTTCTGAAAAGCCGCAC
  ATATAGACAAAACAAAACAAAAATTCCTGAACTGGACAAACAGCAAATACTCAACAGGGT
  TGTTAACCTAGGTAACAGTTCAGTAGTTTAAAGAATCTTTTAGACATCTGGAAGCCTTTC
  TATTCATTCCTCAGTACAGTGTTCCAGCCATCCTGCTTGTTTTTTTCCCTCCAATACCTC
  CCAGAACAGAAACACTTGCATCGAGTCTGTTCCTAAGAACTAGTNTTTGAAAAGAAGCGA
  TGTACAAAAATATTTAACAGAACTATGAAAGATGCAGGANAGGAGGTCTTCTTCGTAGCA
  AAGTAGTCGTTGCTTTGCATGGGTTCCTTTGGATACTCTNCAGGGTTTGTTTATCTGCCC
  CATGAATAACACAGCACCTGTAGAATTATGTCGGATGAAAAACAGAAAGGTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006216
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006216.2, NP_006207.1
• RefSeq Size: 2120 bp
• RefSeq ORF: 1197 bp
• Locus ID: 5270
• UniProt ID: P07093
• Cytogenetics: 2q36.1
• Domains: SERPIN
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
  Transcript Variant: This variant (1) encodes isoform a.