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Home cDNA Clone TrueORF All PDGFRA ORF Clones

PDGFRA (NM_006206) Human cDNA ORF Clone

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Cat. No. Description Price Availability  
RG211740 PDGFRA (GFP-tagged) - Human platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), 10µg
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for PDGFRA (NM_006206)
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TrueORF Data for RG211740
Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3270 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome
Protein Pathways: MAPK signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionEndocytosisFocal adhesionGap junctionMore Pathways >>

Reference Data
RefSeq: NM_006206.3, NP_006197
RefSeq Size: 6405 RefSeq ORF: 3270
LocusID: 5156 Cytogenetic: 4q12 Domains: pkinase, TyrKc, S_TKc, ig, IGc2, IG
Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012].


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