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Home cDNA Clone TrueORF All HES1 ORF Clones

HES1 (NM_005524) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG211709 HES1 (GFP-tagged) - Human hairy and enhancer of split 1, (Drosophila) (HES1), 10µg
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RG211709
Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 843 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Stem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsTranscription FactorsDruggable Genome
Protein Pathways: Notch signaling pathwayMaturity onset diabetes of the young

Reference Data
RefSeq: NM_005524.2, NP_005515
RefSeq Size: 1471 RefSeq ORF: 843
Synonyms : bHLHb39; HES-1; HHL; HRY
LocusID: 3280 Cytogenetic: 3q28-q29 Domains: HLH, ORANGE
Summary: This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008].


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