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Home cDNA Clone TrueORF All SRC ORF Clones

SRC (NM_005417) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG208622 SRC (GFP-tagged) - Human v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 1, 10µg
$590
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for SRC (NM_005417)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG208622
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1611 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Stem cell relevant signaling - JAK/STAT signaling pathwayProtein KinaseES Cell Differentiation/IPSDruggable Genome
Protein Pathways: ErbB signaling pathwayEndocytosisVEGF signaling pathwayFocal adhesionAdherens junctionTight junctionMore Pathways >>

Reference Data
RefSeq: NM_005417.3, NP_005408
RefSeq Size: 4145 RefSeq ORF: 1611
Synonyms : ASV; c-SRC; p60-Src; SRC1
LocusID: 6714 Cytogenetic: 20q12-q13
Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

 

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