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Home cDNA Clone TrueORF All CD86 ORF Clones

CD86 (NM_006889) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG206513 CD86 (GFP-tagged) - Human CD86 molecule (CD86), transcript variant 2, 10µg
$510
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for CD86 (NM_006889)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody
TrueORF Data for RG206513
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 972 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneTranscription FactorsDruggable Genome
Protein Pathways: Cell adhesion molecules (CAMs)Toll-like receptor signaling pathwayType I diabetes mellitusAutoimmune thyroid diseaseSystemic lupus erythematosusAllograft rejectionMore Pathways >>

Reference Data
RefSeq: NM_006889.2, NP_008820
RefSeq Size: 2794 RefSeq ORF: 972
Synonyms : B7-2; B7.2; B70; CD28LG2; LAB72
LocusID: 942 Cytogenetic: 3q21 Domains: IGv, IG
Summary: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

 

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