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Home cDNA Clone TrueORF All GMPS ORF Clones

GMPS (NM_003875) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG204267 GMPS (GFP-tagged) - Human guanine monphosphate synthetase (GMPS), 10µg
$590
2-3 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RG204267
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2082 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Stem cell - Pluripotency
Protein Pathways: Purine metabolismDrug metabolism - other enzymesMetabolic pathways

Reference Data
RefSeq: NM_003875.2, NP_003866
RefSeq Size: 2457 RefSeq ORF: 2082
Synonyms : MLL/GMPS fusion protein; GMP synthase; GMP synthetase; glutamine amidotransferase; guanine monophosphate synthetase; guanosine 5'-monophosphate synthase; guanine monphosphate synthetase
LocusID: 8833 Cytogenetic: 3q24 Domains: GATase, GMP_synt_C
Summary: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008].

 

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