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Home cDNA Clone TrueORF All CTSD ORF Clones

CTSD (NM_001909) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG200719 CTSD (GFP-tagged) - Human cathepsin D (CTSD), 10µg   
$610
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TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
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0 2 weeks
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TrueORF Data for RG200719
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1239 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: ProteaseDruggable Genome
Protein Pathways: Lysosome

Reference Data
RefSeq Explanation: NM_001909.3, NP_001900 RefSeq Size: 2205 RefSeq ORF: 1239
Synonyms : CLN10; CPSD; HEL-S-130P
LocusID: 1509 Cytogenetic: 11p15.5 Domains: asp
Gene Summary: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015].

 

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