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Home cDNA Clone TrueORF All PLA2G1B ORF Clones
TrueORF Gold

PLA2G1B (NM_000928) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC216089 PLA2G1B (Myc-DDK-tagged)-Human phospholipase A2, group IB (pancreas) (PLA2G1B), 10µg
$380
In Stock
RC516089 PLA2G1B (Myc-DDK-tagged)-Human phospholipase A2, group IB (pancreas) (PLA2G1B), (200ug) $500 2~3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC216089L2 Lenti ORF clone of Human phospholipase A2, group IB (pancreas) (PLA2G1B), mGFP tagged

$830 2 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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Also for PLA2G1B (NM_000928)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC216089
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 447 bp
Predicted Protein MW: 16.2 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: Glycerophospholipid metabolismEther lipid metabolismArachidonic acid metabolismLinoleic acid metabolismalpha-Linolenic acid metabolismMetabolic pathwaysMore Pathways >>
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_000928.2, NP_000919
RefSeq Size: 585 RefSeq ORF: 447
Synonyms : PLA2; PLA2A; PPLA2
LocusID: 5319 Cytogenetic: 12q24.31
Summary: This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013].

 

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