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Home cDNA Clone TrueORF All LGR5 ORF Clones

LGR5 (NM_003667) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC212825L2 Lenti ORF clone of Human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), mGFP tagged, 10µg   
$810
2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC512825L2 0 4 weeks
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TrueORF Data for RC212825L2
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Vector: pLenti-C-mGFP   Change vector? Tag: C-terminal mGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2724 bp
Predicted Protein MW: 99.8 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: GPCRTransmembraneDruggable Genome

Reference Data
RefSeq Explanation: NM_003667.2, NP_003658 RefSeq Size: 2880 RefSeq ORF: 2724
Synonyms : FEX; GPR49; GPR67; GRP49; HG38
LocusID: 8549 Cytogenetic: 12q21.1 Domains: 7tm_1, LRRNT, LRR, LRR_TYP, LRR_PS
Gene Summary: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].

 

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