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Home CRISPR-CAS9 KN212698

HDC - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN212698 HDC - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN212698RB HDC - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN212698LP HDC - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN212698BN HDC - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN212698, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN212698G1, HDC gRNA vector 1 in pCas-Guide vector
KN212698G2, HDC gRNA vector 2 in pCas-Guide vector
KN212698D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001306146NM_002112XM_017022094XM_017022095XM_017022096XM_017022097XM_017022098XM_017022099
Synonyms:
Summary: This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010].

Learn more about CRISPR?

Diagram-Gene Editing RecombII


 

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