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Home CRISPR-CAS9 KN211493

CACNB2 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN211493 CACNB2 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN211493RB CACNB2 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN211493LP CACNB2 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN211493BN CACNB2 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN211493, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN211493G1, CACNB2 gRNA vector 1 in pCas-Guide vector
KN211493G2, CACNB2 gRNA vector 2 in pCas-Guide vector
KN211493D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_000724NM_001167945NM_201570NM_201571NM_201572NM_201590NM_201593NM_201596NM_201597XM_005252588XM_005252591XM_006717502XM_011519659XM_017016625XR_001747198
Synonyms: CACNLB2; CAVB2; MYSB
Summary: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. [UniProtKB/Swiss-Prot Function]

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Diagram-Gene Editing RecombII


 

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