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Home CRISPR-CAS9 KN210515

DFNA5 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN210515 DFNA5 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN210515RB DFNA5 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN210515LP DFNA5 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN210515BN DFNA5 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN210515, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN210515G1, DFNA5 gRNA vector 1 in pCas-Guide vector
KN210515G2, DFNA5 gRNA vector 2 in pCas-Guide vector
KN210515D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001127453NM_001127454NM_004403XM_017011802
Synonyms: ICERE-1
Summary: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Learn more about CRISPR?

Diagram-Gene Editing RecombII


 

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