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Home CRISPR-CAS9 KN209053

TMOD2 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN209053 TMOD2 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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Also for TMOD2 (Locus ID 29767)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody
SKU Description Donor Vector Price Availability  
KN209053RB TMOD2 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN209053LP TMOD2 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN209053BN TMOD2 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN209053, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN209053G1, TMOD2 gRNA vector 1 in pCas-Guide vector
KN209053G2, TMOD2 gRNA vector 2 in pCas-Guide vector
KN209053D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001142885NM_014548XM_017022089
Synonyms: N-TMOD; NTMOD
Summary: This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008].

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Diagram-Gene Editing RecombII


 

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