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Home CRISPR-CAS9 KN208485

MOCS2 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN208485 MOCS2 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN208485RB MOCS2 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN208485LP MOCS2 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN208485BN MOCS2 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN208485, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
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Kit Components
KN208485G1, MOCS2 gRNA vector 1 in pCas-Guide vector
KN208485G2, MOCS2 gRNA vector 2 in pCas-Guide vector
KN208485D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_004531NM_176806NM_183418
Synonyms: MCBPE; MOCO1; MOCODB; MPTS
Summary: Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008]

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Diagram-Gene Editing RecombII


 

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