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Home CRISPR-CAS9 KN207714

KCNH7 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN207714 KCNH7 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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Also for KCNH7 (Locus ID 90134)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody
SKU Description Donor Vector Price Availability  
KN207714RB KCNH7 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN207714LP KCNH7 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN207714BN KCNH7 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN207714, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN207714G1, KCNH7 gRNA vector 1 in pCas-Guide vector
KN207714G2, KCNH7 gRNA vector 2 in pCas-Guide vector
KN207714D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_033272NM_173162XM_011512109XM_017005218XM_017005219XM_017005220XM_017005221
Synonyms: ERG3; HERG3; Kv11.3
Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Diagram-Gene Editing RecombII


 

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