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Home CRISPR-CAS9 KN203667

UTP4 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN203667 UTP4 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN203667RB CIRH1A - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN203667LP CIRH1A - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN203667BN CIRH1A - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN203667, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN203667G1, UTP4 gRNA vector 1 in pCas-Guide vector
KN203667G2, UTP4 gRNA vector 2 in pCas-Guide vector
KN203667D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001318391NM_032830XM_005256205XR_001752011
Synonyms: CIRH1A; CIRHIN; NAIC; TEX292
Summary: This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

Learn more about CRISPR?

Diagram-Gene Editing RecombII


 

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