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Home CRISPR-CAS9 KN204034

CA12 - human gene knockout kit via CRISPR

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Specifications  Citations (1)  Validation Data  FAQ
SKU Description Price Availability Manual  
KN204034 CA12 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN204034RB CA12 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN204034LP CA12 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN204034BN CA12 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN204034, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN204034G1, CA12 gRNA vector 1 in pCas-Guide vector
KN204034G2, CA12 gRNA vector 2 in pCas-Guide vector
KN204034D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001218NM_001293642NM_206925NR_135511
Synonyms: CA-XII; CAXII; HsT18816; T18816
Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014].

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Diagram-Gene Editing RecombII


 

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