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Home Antibody All anti-CDH3 antibodies

Anti-CDH3 TRUEMAB Antibody Clone OTI2D5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA506403 CDH3 (P cadherin) mouse monoclonal antibody, clone OTI2D5 (formerly 2D5) 100ul $379 In Stock
LC400683 CDH3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506403 Carrier-free (BSA/glycerol-free) CDH3 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(6)
IF(2)

OriGene Data

ImmunogenFull length human recombinant protein of human CDH3(NP_001784) produced in HEK293T cell.
Clone NameClone OTI2D5 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:4000, IHC 1:150, IF 1:100,
Predicted MW Explanation 88.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cadherin 3, type 1, P-cadherin (placental) (CDH3)
Alternative NameCDHP; HJMD; PCAD
Database LinkNP_001784
Entrez Gene 1001 Human
FunctionThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008].
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH3 (RC207346, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH3.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506403)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506403)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506403)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506403)
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Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506403)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506403)
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Anti-CDH3 mouse monoclonal antibody (TA506403) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CDH3(RC207346).
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Immunofluorescent staining of HeLa cells using anti-CDH3 mouse monoclonal antibody (TA506403).
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