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Home Antibody All anti-SOCS3 antibodies

Anti-SOCS3 TRUEMAB Antibody clone 11C5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502959
  • SOCS3 mouse monoclonal antibody, clone 11C5
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401300) , 20ug Explanation
100ul 325 In Stock
CF502959
  • Carrier-free (BSA/glycerol-free) SOCS3 mouse monoclonal antibody, clone 11C5
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IF(1)
FC(2)
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Also for SOCS3 (NM_003955)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell.
Clone Nameclone 11C5 IsotypeIgG1
Species ReactivityHuman Concentration0.99 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 24.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens suppressor of cytokine signaling 3 (SOCS3)
Alternative NameATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Database LinkNP_003946
Entrez Gene 9021 Human
FunctionThis gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq].
Related PathwayDruggable Genome Ubiquitin mediated proteolysisJak-STAT signaling pathwayInsulin signaling pathwayAdipocytokine signaling pathwayType II diabetes mellitus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOCS3 (RC209305, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SOCS3.
IF Image
Anti-SOCS3 mouse monoclonal antibody (TA502959) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SOCS3(RC209305 ).
FC Image
Flow cytometric Analysis of Hela cells, using anti-SOCS3 antibody(TA502959),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-SOCS3 antibody(TA502959),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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