TMEM88 Rabbit Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human transmembrane protein 88 (TMEM88), 20 µg
USD 867.00
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Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | TMEM88 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88. |
Formulation | TMEM88 Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | TMEM88 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | transmembrane protein 88 |
Database Link | |
Background | TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner. |
Synonyms | FLJ20025; MGC71744 |
Reference Data | |
Protein Families | Transmembrane |
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