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Home Antibody All anti-NKX2-2 antibodies

Anti-NKX2-2 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319689 Rabbit Polyclonal NKX2-2 Antibody 100ug $325 In Stock
LC419283 NKX2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for NKX2-2 (NM_002509)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenNKX2-2 antibody was raised against a 19 amino acid synthetic peptide near the center of human NKX2-2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferNKX2-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NKX2-2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NK2 homeobox 2 (NKX2-2)
Alternative NameNKX2.2; NKX2B
Database LinkNP_002500
Entrez Gene 4821 Human
Entrez Gene 18088 Mouse
Entrez Gene 366214 Rat
FunctionNKX2-2 Antibody: NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature α-, β- and PP cells, and in NKX2-2-null mice embryos, all β-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.
Related PathwayTranscription Factors Maturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of NKX2-2 in rat kidney tissue lysate with NKX2-2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of NKX2-2 in human kidney tissue with NKX2-2 antibody at 2.5 ug/mL.
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Immunofluorescence of NKX2-2 in human kidney tissue with NKX2-2 antibody at 20 ug/mL.
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