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Anti-CTSB Antibody EPR4323
Also for CTSB (NM_001908)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 28 and 157 of Cathepsin B|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC/IF: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt.
|Homo sapiens cathepsin B (CTSB), transcript variant 1|
Entrez Gene 1508 Human
|Cathepsin B is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of Cathepsin B, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors (1).|
|ProteaseDruggable Genome LysosomeAntigen processing and presentation|
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Western blot - Anti-Cathepsin B antibody [EPR4323]; All lanes : Anti-Cathepsin B antibody [EPR4323] at 1/1000 dilution.Lane 1 : HT1080 cell lysate .Lane 2 : A375 cell lysate.Lane 3 : SW480 cell lysate .Lane 4 : A549 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 38 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cathepsin B antibody [EPR4323]; TA310375, at a 1/50 dilution, staining Cathepsin B in paraffin-embedded Human kidney tissue by immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cathepsin B antibody [EPR4323]; TA310375, at a 1/50 dilution, staining Cathepsin B in paraffin-embedded Human papillary carcinoma tissue by immunohistochemistry.
Immunocytochemistry/ Immunofluorescence - Anti-Cathepsin B antibody [EPR4323]; TA310375, at a 1/50 dilution, staining Cathepsin B (red) in HeLa cells by immunofluorescence. DNA is marked in blue.