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Home Antibody All anti-CTSB antibodies

Anti-CTSB Antibody EPR4323

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310375
  • Rabbit Monoclonal antibody against Cathepsin B (CTSB)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419666) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(2)
IF(1)
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Also for CTSB (NM_001908)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 28 and 157 of Cathepsin B
Clone NameEPR4323 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC/IF: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens cathepsin B (CTSB), transcript variant 1
Alternative NameAPPS; CPSB
Database LinkNP_001899
FunctionCathepsin B is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of Cathepsin B, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors (1).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Cathepsin B antibody [EPR4323]; All lanes : Anti-Cathepsin B antibody [EPR4323] at 1/1000 dilution.Lane 1 : HT1080 cell lysate .Lane 2 : A375 cell lysate.Lane 3 : SW480 cell lysate .Lane 4 : A549 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 38 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cathepsin B antibody [EPR4323]; TA310375, at a 1/50 dilution, staining Cathepsin B in paraffin-embedded Human kidney tissue by immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cathepsin B antibody [EPR4323]; TA310375, at a 1/50 dilution, staining Cathepsin B in paraffin-embedded Human papillary carcinoma tissue by immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Cathepsin B antibody [EPR4323]; TA310375, at a 1/50 dilution, staining Cathepsin B (red) in HeLa cells by immunofluorescence. DNA is marked in blue.

 

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