Home Antibody All anti-PRKCA antibodies
Also for PRKCA (NM_002737)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 220 of Human PRKCA|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens protein kinase C, alpha (PRKCA)|
|AAG6; PKC-alpha; PKCA; PRKACA|
|Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq]|
EGFR1 Signaling Pathway
MAPK signaling pathway
Wnt Signaling Pathway
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Sample (30 ug of whole cell lysate) A: H1299 (anti-PRKCA antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded Colon ca, using PKC alpha(anti-PRKCA antibody) antibody at 1:500 dilution.