Home Antibody All anti-TGFBR3 antibodies
Also for TGFBR3 (NM_003243)
|Recombinant fragment corresponding to a region within amino acids 88 and 314 of TGF beta Receptor III (Uniprot ID#Q03167)|
|Human (Predicted: Mouse, Pig)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (87%), Pig (89%)
|Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 1|
Entrez Gene 7049 Human
Entrez Gene 21814 Mouse
|Transforming growth factor (TGF)-beta is a multifunctional cytokine that modulates several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. Three TGF-beta forms are encoded by separate genes: TGFB1 (MIM 190180), TGFB2 (MIM 190220), and TGFB3 (MIM 190230). The diverse effects of TGF-beta are mediated by the TGF-beta receptors and cell surface-binding proteins. Three TGF-beta receptors exist: type I (TGFBR1; MIM 190181), type II (TFGBR2; MIM 190182), and type III (TGFBR3). TGFBR3 is a glycoprotein that binds TGFB and exists in both a membrane-bound and a soluble form (Johnson et al., 1995 [PubMed 8530052]).[supplied by OMIM]|
|Secreted ProteinTransmembraneDruggable Genome |
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Sample (30 ug of whole cell lysate). A: THP-1. 7.5% SDS PAGE. TA308670 diluted at 1:1000.