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Home Antibody All anti-COL1A2 antibodies

Anti-COL1A2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308423
  • Rabbit polyclonal antibody to Collagen I alpha2 (collagen, type I, alpha 2)
100ul 325 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1057 and 1339 of Collagen I alpha2
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.4mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens collagen, type I, alpha 2 (COL1A2)
Alternative NameOI4
Database LinkNP_000080
FunctionThis gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]
Related Pathway
Focal Adhesion
Hemostasis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate) A: 293T B: A431 (anti-COL1A2 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using Collagen I alpha2(anti-COL1A2 antibody) antibody at 1:200 dilution.

 

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