GADD45G Rabbit Polyclonal Antibody

CAT#: TA308278

Rabbit Polyclonal antibody to GADD45 gamma (growth arrest and DNA-damage-inducible, gamma)

Product Images

Sample (30 ug of whole cell lysate). A: Hela. 12% SDS PAGE. TA308278 diluted at 1:1000.

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  Immunofluorescence analysis of methanol-fixed HeLa, using GADD45 gamma (TA308278) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Rat, Pig, Bovine, Rhesus Monkey, X. tropicalis, Mouse)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 96 and 159 of GADD45G (Uniprot ID#O95257)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 17 kDa
• Gene Name: growth arrest and DNA damage inducible gamma
• Database Link:
  NP_006696
  Entrez Gene 23882 MouseEntrez Gene 291005 RatEntrez Gene 10912 Human
  UniProt ID O95257
• Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq]
• Synonyms: CR6; DDIT2; GADD45gamma; GRP17
• Note: Seq homology of immunogen across species: Mouse (93%), Rat (93%), Xenopus Tropicalis (86%), Pig (93%), Rhesus Monkey (100%), Bovine (93%)

Reference Data

• Protein Pathways: Cell cycle, MAPK signaling pathway, p53 signaling pathway