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Home Antibody All anti-GCM2 antibodies

Anti-GCM2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308011 Rabbit polyclonal antibody to GCM2 (glial cells missing homolog 2 (Drosophila)) 100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 236 and 506 of GCM2 (Uniprot ID#O75603)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.75mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 57kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens glial cells missing homolog 2 (Drosophila) (GCM2)
Alternative NameGCMB; hGCMb
Database LinkNP_004743
Entrez Gene 9247 Human
FunctionThis gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. TA308011 diluted at 1:1000.
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