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Home Antibody All anti-ADRBK2 antibodies

Anti-ADRBK2 Antibody EPR2041(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307821
  • Rabbit monoclonal antibody against GRK3(clone EPR2041(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417480) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ADRBK2 (NM_005160)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GRK3 was used as an immunogen.
Clone NameEPR2041(2) IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens adrenergic, beta, receptor kinase 2 (ADRBK2)
Alternative NameBARK2; GRK3
Database LinkNP_005151
FunctionThe beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, GRK3 (beta adrenergic receptor kinase 2) has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - GRK3 antibody [EPR2041(2)]; All lanes : Anti-GRK3 antibody [EPR2041(2)] at 1/1000 dilution.Lane 1 : U937 cell lysate.Lane 2 : Ramos cell lysate.Lane 3 : HL-60 cell lysate.Lane 4 : Molt-4 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 80 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GRK3 antibody [EPR2041(2)]; TA307821, at 1/100 dilution, staining GRK3 in Human brain tissue by immunohistochemistry.

 

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