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Home Antibody All anti-ADRBK2 antibodies

Anti-ADRBK2 Antibody EPR2041(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307821
  • Rabbit monoclonal antibody against GRK3(clone EPR2041(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417480) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ADRBK2 (NM_005160)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GRK3 was used as an immunogen.
Clone NameEPR2041(2) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens adrenergic, beta, receptor kinase 2 (ADRBK2)
Alternative NameBARK2; GRK3
Database LinkNP_005151
Entrez Gene 157 Human
FunctionThe beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, GRK3 (beta adrenergic receptor kinase 2) has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
Related PathwayProtein KinaseDruggable Genome Chemokine signaling pathwayEndocytosisOlfactory transduction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - GRK3 antibody [EPR2041(2)]; All lanes : Anti-GRK3 antibody [EPR2041(2)] at 1/1000 dilution.Lane 1 : U937 cell lysate.Lane 2 : Ramos cell lysate.Lane 3 : HL-60 cell lysate.Lane 4 : Molt-4 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 80 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GRK3 antibody [EPR2041(2)]; TA307821, at 1/100 dilution, staining GRK3 in Human brain tissue by immunohistochemistry.

 

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