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Home Antibody All anti-GRK6 antibodies

Anti-GRK6 Antibody EPR2046(2)

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SKU Description Amount Price Availability*  
TA307818
  • Rabbit monoclonal antibody against GRK6(clone EPR2046(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419550) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GRK6 was used as an immunogen.
Clone NameEPR2046(2) IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens G protein-coupled receptor kinase 6 (GRK6), transcript variant 2
Alternative NameGPRK6
Database LinkNP_002073
Entrez Gene 2870 Human
Entrez Gene 26385 Mouse
FunctionG protein-coupled receptor kinases (GRK’s) phosphorylate ligand-activated G protein-coupled receptors on serine and threonine residues within the carboxy-terminal tail and intracellular loops, a process that is accompanied by the recruitment of beta-Arrestins (1). GRK6 is a member of the guanine nucleotide-binding protein GRK subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors, thus initiating their deactivation (2).
Related PathwayProtein KinaseDruggable Genome Chemokine signaling pathwayEndocytosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - GRK6 antibody [EPR2046(2)]; All lanes : Anti-GRK6 antibody [EPR2046(2)] at 1/1000 dilution.Lane 1 : U937 cell lysate.Lane 2 : Ramos cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 66 kDa.

 

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