OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-CD3G antibodies

Anti-CD3G Antibody EPR4516

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307756
  • Rabbit monoclonal antibody against CD3 gamma(clone EPR4516)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400019) , 20ug
100ul 325 In Stock
Add to Shopping Cart
WB(2)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human CD3 gamma was used as an immunogen.
Clone NameEPR4516 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:500 - 1:1000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens CD3g molecule, gamma (CD3-TCR complex) (CD3G)
Alternative NameCD3-GAMMA; IMD17; T3G
Database LinkNP_000064
FunctionCD3 is composed of five invariant polypeptide chains that associate to form three dimers. The five invariant chains of CD3 are labeled gamma, delta, epsilon, zeta, and eta (3). CD3 forms complex with the T cell antigen receptor (TCR) (1). Antigen binding to the TCR leads to IL-2 secretion via activation of a tyrosine phosphorylation pathway and a phospholipase C (PLC) pathway, in turn activating protein kinase C (1,2). Defects in this protein are associated with T cell immunodeficiency (4).
Related Pathway
Hematopoietic cell lineage

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD3G antibody [EPR4516]; All lanes : Anti-CD3G antibody [EPR4516] at 1/1000 dilution.Lane 1 : Human tonsil lysate.Lane 2 : Human fetal thymus lysate.Lane 3 : HuT-78 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 20 kDa.
WB Image
Western blot - CD3G antibody [EPR4516]; Anti-CD3G antibody [EPR4516] at 1/1000 dilution + Jurkat cell lysate at 10 µg.Predicted band size : 20 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD3G antibody [EPR4516]; TA307756, at 1/100 dilution, staining CD3G in paraffin-embedded Human tonsil tissue by Immunohistochemistry.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title