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Home Antibody All anti-CD3G antibodies

Anti-CD3G Antibody EPR4516

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SKU Description Amount Price Availability*  
TA307756
  • Rabbit monoclonal antibody against CD3 gamma(clone EPR4516)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400019) , 20ug Explanation
100ul $325 2 Weeks
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WB(2)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human CD3 gamma was used as an immunogen.
Clone NameEPR4516 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:500 - 1:1000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens CD3g molecule, gamma (CD3-TCR complex) (CD3G)
Alternative NameCD3-GAMMA; IMD17; T3G
Database LinkNP_000064
Entrez Gene 917 Human
FunctionCD3 is composed of five invariant polypeptide chains that associate to form three dimers. The five invariant chains of CD3 are labeled gamma, delta, epsilon, zeta, and eta (3). CD3 forms complex with the T cell antigen receptor (TCR) (1). Antigen binding to the TCR leads to IL-2 secretion via activation of a tyrosine phosphorylation pathway and a phospholipase C (PLC) pathway, in turn activating protein kinase C (1,2). Defects in this protein are associated with T cell immunodeficiency (4).
Related PathwayTransmembraneDruggable Genome Hematopoietic cell lineageT cell receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - CD3G antibody [EPR4516]; All lanes : Anti-CD3G antibody [EPR4516] at 1/1000 dilution.Lane 1 : Human tonsil lysate.Lane 2 : Human fetal thymus lysate.Lane 3 : HuT-78 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 20 kDa.
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Western blot - CD3G antibody [EPR4516]; Anti-CD3G antibody [EPR4516] at 1/1000 dilution + Jurkat cell lysate at 10 ug.Predicted band size : 20 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD3G antibody [EPR4516]; TA307756, at 1/100 dilution, staining CD3G in paraffin-embedded Human tonsil tissue by Immunohistochemistry.
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