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Anti-FCGR3A Antibody EPR4333
Also for FCGR3A (NM_000569)
|A synthetic peptide corresponding to residues in human CD16a was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:50000 - 1:20000; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A), transcript variant 1|
|CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20|
|CD16a is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. The receptor encoded by CD16a is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide. Mutations in CD16a have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia (1).|
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Western blot - CD16 antibody [EPR4333]; All lanes : Anti-CD16 antibody [EPR4333] at 1/50000 dilution.Lane 1 : U937 cell lysate.Lane 2 : THP-1 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : K562 cell lysate.Lane 5 : C6 cell lysate.Lane 6 : Raw264.7 cell lysate.Lane 7 : PC-12 cell lysates .Lysates/proteins at 10 µg per lane.Predicted band size : 29 kDa.Observed band size : 45 kDa .