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Home Antibody All anti-AQP5 antibodies

Anti-AQP5 Antibody EPR3747

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307525
  • Rabbit monoclonal antibody against Aquaporin 5 (clone EPR3747 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400622) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(4)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Aquaporin 5 was used as an immunogen.
Clone NameEPR3747 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; ICC/IF: Use at an assay dependent concentration
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens aquaporin 5 (AQP5)
Alternative NameAQP-5; PPKB
Database LinkNP_001642
Entrez Gene 362 Human
FunctionAquaporin 5 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions (1). It is expressed in epithelia of lung, cornea, and various secretory glands; sites where extracellular osmolality is known to fluctuate (2). Expression of Aquaporin 5 may have pathophysiological implications attributed to a dysfunctional water regulation by Aquaporin 5such as endolymphatic hydrops (i.e. in Meniere's disease) or sensorineural hearing loss (i.e. in Sjögren's syndrome) (3). Up-regulation of Aquaporin 5 may be involved in differentiation of human gastric cancer cells (4).
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Aquaporin 5 antibody [EPR3747]; All lanes : Anti-Aquaporin 5 antibody [EPR3747] at 1/1000 dilution.Lane 1 : Fetal lung lysate.Lane 2 : SW480 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/1000 dilution.Predicted band size : 28 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Aquaporin 5 antibody [EPR3747]; TA307525 at 1/100 dilution, staining Aquaporin 5 in paraffin embedded Human lung tissue
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Aquaporin 5 antibody [EPR3747](TA307525); TA307525 showing positive staining in Normal colon tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Aquaporin 5 antibody [EPR3747](TA307525); TA307525 showing positive staining in Normal stomach tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Aquaporin 5 antibody [EPR3747](TA307525); TA307525 showing negative staining in Normal brain tissue.

 

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