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Anti-TDGF1 Antibody EPNCIR106A
Also for TDGF1 (NM_003212)
|A synthetic peptide corresponding to residues in human Cripto 1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IHC-P.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens teratocarcinoma-derived growth factor 1 (TDGF1), transcript variant 1|
|CR; CRGF; CRIPTO|
|Cripto 1, also known as Teratocarcinoma-derived growth factor 1 (TDGF1), is a member of the EGF-CFC family that is required for proper laterality development in humans (1, 2). It is an obligate coreceptor involved in the NODAL ligand signaling pathway, a developmental program implicated in midline, forebrain, and left-right axis development (2). Thus, Cripto 1 could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (1). It also increases migration of cells in vitro (3). The Cripto 1 gene is expressed in embryonic stem (ES) cells and during the early phases of embryo development (4). Furthermore, Cripto 1 is expressed at high levels in the majority of different types of human carcinomas including breast, colon, and lung (5).|
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Western blot - Cripto1 antibody [EPNCIR106A]; Anti-Cripto1 antibody [EPNCIR106A] at 1/1000 dilution + NCCIT cell lysate at 10 µg.Predicted band size : 21 kDa.Observed band size : 21 kDa.