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Home Antibody All anti-DLK1 antibodies

Anti-DLK1 Antibody EPR3486(2)

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307339
  • Rabbit monoclonal antibody against DLK(clone EPR3486(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401257) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for DLK1 (NM_003836)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DLK was used as an immunogen.
Clone NameEPR3486(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens delta-like 1 homolog (Drosophila) (DLK1)
Alternative NameDelta1; DLK; DLK-1; FA1; pG2; Pref-1; PREF1; ZOG
Database LinkNP_003827
FunctionDelta-like protein (DLK) is a transmembrane protein characterized by six epidermal growth factor (EGF)-like repeat motifs (1). As a member related to the Notch/Delta/Serrate ligand family of proteins, it inhibits preadipocyte differentiation (1). DLK may also have a role in cell differentiation processes such as adipogenesis, hematopoiesis, and neuroendocrine differentiation (2). In normal B cell development, it influences cell-cell interactions between stromal cells and pro-B cells in vitro (3). DLK is found within the stromal cells in close contact to the vascular structure of the placenta, adrenal cortex, and pancreas; additionally, it is located in the beta cells of the islets of Langerhans in the adult pancreas (4). It is also found in some forms of neuroendocrine lung tumor tissue (3).
Related Pathway
Adipogenesis

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WB Image
Western blot - DLK antibody [EPR3486(2)]; All lanes : Anti-DLK antibody [EPR3486(2)] at 1/1000 dilution.Lane 1 : JAR cell lysate.Lane 2 : SH SY5Y cell lysate.Lane 3 : NCCIT cell lysate.Lane 4 : A549 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 50 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DLK antibody [EPR3486(2)]; TA307339 at 1/100 dilution staining DLK in Human Placenta by Immunohistochemistry, Paraffin-embedded tissue.

 

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