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Anti-BAG2 Antibody EPR3567


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307310 Rabbit monoclonal antibody against Bag-2 (clone EPR3567 ) 100ul $325 In Stock
LC418098 BAG2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-terminus of human Bag-2 was used as immunogen.
Clone NameEPR3567 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsFC: 1:60, ICC: 1:100 - 250, IHC: 1:100, IP: 1:10, WB: 1:1000 - 5000,
Predicted MW Explanation 24 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens BCL2-associated athanogene 2 (BAG2)
Alternative NameBAG-2; dJ417I1.2
Database LinkNP_004273
Entrez Gene 9532 Human
FunctionBAG-2 is a member of a family of BAG-related proteins (BAG-2, BAG-3, BAG-4, BAG-5). BAG-family proteins may play a role in providing opportunities for specification and diversification of Heat Shock Protein (Hsp70) chaperone functions. Hsp70 family molecular chaperones play critical roles in protein folding and trafficking in all eukaryotic cells. BAG-1 binds the ATPase domains of Hsp70 and Hsc70, modulating their chaperone activity and functioning as a competitive antagonist of the co-chaperone Hip. BAG-2 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner (1).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - BAG2 antibody [EPR3567]; All lanes : Anti-BAG2 antibody [EPR3567] at 1/5000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 24 kDa.Observed band size : 24 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - BAG2 antibody [EPR3567]; TA307310, at 1/100 dilution, staining BAG2 in human ovarian carcinoma by Immunohistochemistry using paraffin-embedded tissue.


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