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Anti-ETS1 Antibody EPR546(2)


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against ETS1(clone EPR546(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401606) , 20ug Explanation
100ul $325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ETS1 was used as an immunogen.
Clone NameEPR546(2) IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog 1 (ETS1), transcript variant 2
Alternative NameETS-1; EWSR2; p54
Database LinkNP_005229
Entrez Gene 2113 Human
Entrez Gene 23871 Mouse
FunctionETS transcriptions factors, such as ETS1, regulate numerous proteins and are involved in stem cell development, cell senescence and death, and tumorigenesis (1). Furthermore, it regulates the expression of several angiogenic and extracellular matrix remodeling factors promoting an invasive phenotype (2). The conserved ETS domain within ETS1 is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target proteins (2). ETS-1 is expressed in a variety of cells, including endothelial cells, vascular smooth muscle cells and epithelial cells (2).
Related PathwayTranscription FactorsDruggable Genome Dorso-ventral axis formationPathways in cancerRenal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ETS1 antibody [EPR546(2)]; All lanes : Anti-ETS1 antibody [EPR546(2)] at 1/1000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : Daudi cell lysate.Lane 3 : Molt-4 cell lysate.Lane 4 : PBMC lysate.Lane 5 : HepG2 cell lysate.Lane 6 : Jurkat cell lysate.Lane 7 : Saos-2 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 50 kDa.


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