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Home Antibody All anti-BFAR antibodies

Anti-BFAR Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306918
  • Rabbit Polyclonal BFAR Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402568) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenBFAR antibody was raised against a 14 amino acid peptide near the carboxy terminus of human BFAR.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens bifunctional apoptosis regulator (BFAR)
Alternative NameBAR; RNF47
Database LinkNP_057645
FunctionThe bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
Related Pathway

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WB Image
Western blot analysis of BFAR in human kidney tissue lysate with BFAR antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of BFAR in mouse kidney tissue with BFAR antibody at 5 ug/mL.
IF Image
Immunofluorescence of BFAR in mouse kidney tissue with BFAR antibody at 20 ug/mL.

 

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