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Home Antibody All anti-POFUT1 antibodies

Anti-POFUT1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306631
  • Rabbit Polyclonal POFUT1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC414612) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for POFUT1 (NM_015352)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPOFUT1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human POFUT1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens protein O-fucosyltransferase 1 (POFUT1), transcript variant 1
Alternative NameDDD2; FUT12; O-Fuc-T; O-FucT-1; O-FUT; OFUCT1
Database LinkNP_056167
FunctionPOFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch; mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling. At least two isoforms of POFUT1 are known to exist. This antibody is predicted to not cross-react with POFUT2.
Related Pathway
Delta-Notch Signaling Pathway

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WB Image
Western blot analysis of POFUT1 in human heart tissue lysate with POFUT1 antibody at (A) 0.5 and (B) 1 ug/ml.
IHC Image
Immunohistochemistry of POFUT1 in human heart tissue with POFUT antibody at 2.5 ug/ml.

 

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