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Home Antibody All anti-BCAP31 antibodies

Anti-BCAP31 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306278 Rabbit Polyclonal BAP31 Antibody 100ug $325 3-7 Days
LC427957 BCAP31 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for BCAP31 (NM_001139441)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenBAP31 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human BAP31.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens B-cell receptor-associated protein 31 (BCAP31), transcript variant 3
Alternative Name6C6-AG; BAP31; CDM; DDCH; DXS1357E
Database LinkNP_001132913
Entrez Gene 10134 Human
Entrez Gene 27061 Mouse
Entrez Gene 293852 Rat
FunctionBap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18 (3,4). It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria (5). Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death (5).
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of BAP31 in Ramos cell lysate with BAP31 antibody at (A) 0.5, (B) 1 and (C) 2ug/ml.
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Immunohistochemistry of BAP31 in rat lung tissue with BAP31 antibody at 2 ug/ml.
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